Detalhe da pesquisa
1.
An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential.
Cell
; 173(6): 1413-1425.e14, 2018 05 31.
Artigo
Inglês
| MEDLINE | ID: mdl-29754815
2.
A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells.
Mol Cell Proteomics
; 17(10): 1892-1908, 2018 10.
Artigo
Inglês
| MEDLINE | ID: mdl-29970458
3.
Comparative Network Reconstruction using mixed integer programming.
Bioinformatics
; 34(17): i997-i1004, 2018 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30423075
4.
Modelling signalling networks from perturbation data.
Bioinformatics
; 34(23): 4079-4086, 2018 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29931053
5.
Identifying mutant-specific multi-drug combinations using comparative network reconstruction.
iScience
; 25(8): 104760, 2022 Aug 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35992065
6.
RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS-mutant colorectal cancer.
Transl Oncol
; 13(2): 201-211, 2020 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-31865182
7.
Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours.
Nat Commun
; 11(1): 3157, 2020 06 22.
Artigo
Inglês
| MEDLINE | ID: mdl-32572029
8.
Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux.
Sci Rep
; 8(1): 5576, 2018 04 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29615663
9.
A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers.
Genome Med
; 10(1): 90, 2018 11 27.
Artigo
Inglês
| MEDLINE | ID: mdl-30482246
10.
MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.
Cell Res
; 28(7): 719-729, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29795445
11.
Evolutionary pressures on microbial metabolic strategies in the chemostat.
Sci Rep
; 6: 29503, 2016 07 06.
Artigo
Inglês
| MEDLINE | ID: mdl-27381431
12.
Correction to: A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers.
Genome Med
; 13(1): 24, 2021 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33568196
13.
Binding proteins enhance specific uptake rate by increasing the substrate-transporter encounter rate.
FEBS J
; 282(12): 2394-407, 2015 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-25846030
14.
How fast-growing bacteria robustly tune their ribosome concentration to approximate growth-rate maximization.
FEBS J
; 282(10): 2029-44, 2015 May.
Artigo
Inglês
| MEDLINE | ID: mdl-25754869
15.
How biochemical constraints of cellular growth shape evolutionary adaptations in metabolism.
Genetics
; 194(2): 505-12, 2013 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-23535382